ONCE-DAILY ORAL DOSING
Dosing schedule and administration
START EARLY WITH ERLEADA® TO HELP HIM BE THERE™
The recommended dose of ERLEADA® is 240 mg (four 60 mg tablets) administered orally, once daily1
Tablets shown are not actual size.
No initial dose adjustments needed for renal or hepatic impairment*
*ERLEADA® has not been evaluated in patients with severe renal or hepatic impairment.
No need for co-administration of a corticosteroid
Can be taken with or without food. Tablets should be swallowed whole1
Alternate dosing for those who have difficulty swallowing tablets:
- Patients can be instructed to mix their dose of ERLEADA® with applesauce or discuss other options with a nurse educator1
Patients should also receive a GnRH analog concurrently or should have had a bilateral orchiectomy.1
If Grade 3 or greater adverse reactions, or other intolerable adverse reactions occur, withhold ERLEADA®. Consider permanent discontinuation of ERLEADA® for Grade 3 or 4 cerebrovascular and ischemic cardiovascular events. Permanently discontinue ERLEADA® for confirmed SCARs or for other Grade 4 skin reactions. For other adverse reactions, when symptoms improve to less than or equal to Grade 1 or original grade, resume ERLEADA® at the same dose or a reduced dose (180 mg or 120 mg), if warranted.1
ALTERNATE METHOD OF ADMINISTRATION
For patients who have difficulty swallowing tablets, ERLEADA® may be taken by mixing the recommended dose in applesauce. The following instructions are included in Section 2.3 of the full Prescribing Information for ERLEADA®.
1.Mix whole ERLEADA® tablets in 4 ounces (120 mL) of applesauce by stirring. Do not crush the tablets.
2.Wait 15 minutes, stir the mixture.
3.Wait another 15 minutes, stir the mixture until tablets are dispersed (well mixed with no chunks remaining).
4.Using a spoon, swallow the mixture right away.
5.Rinse the container with 2 ounces (60 mL) of water and immediately drink the contents. Repeat the rinse with 2 ounces (60 mL) of water a second time to ensure the whole dose is taken.
Consume the mixture within 1 hour of preparation. Do not store ERLEADA® that is mixed with applesauce.
Janssen Compass™ is a free, personalized patient support program that can help your patients get started with their treatment and stay on track. Look to Janssen Compass™ to help them navigate cost support options, as well as one-on-one guidance in learning about educational resources they need to feel confident on their Janssen therapy.
Get information, guidance, and support
- ERLEADA® [Prescribing Information]. Horsham, PA: Janssen Biotech, Inc.